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Irvine Firm to Develop Insomnia Drug

SPECIAL TO THE TIMES

Monsanto Co.’s Searle unit said it will team up with Irvine-based CoCensys Inc. in a multimillion-dollar effort to develop a drug to treat insomnia.

Searle will pay $10 million initially to CoCensys, a small biopharmaceutical research and development company, but the arrangement could generate $80 million in licensing fees and other Searle contributions toward development costs over the next six years, the companies said.

Officials at CoCensys said the deal marks the first time a major pharmaceutical house has invested in the synthetic drug compounds called Epalons, which were developed by the two research doctors who founded the company in 1989.

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“This is validation from the industry,” said CoCensys spokeswoman Christi Foster.

The 150-employee company develops drugs to treat neurological and psychiatric disorders, but none of its own drug products has been approved for marketing.

The companies hope to produce a marketable drug in about six years, they said.

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